Filtering Facepiece Respirators (FFRs) are typically used by workers, including first responders and healthcare professionals, for short, infrequent periods of time to protect against potential airborne transmissible diseases. However, during widespread respiratory infectious disease outbreaks, there may be a need to implement respirator extended use practices due to an inadequate supply of FFRs. Skin irritation caused by disposable FFR use for extended periods of time has been documented during past outbreaks of respiratory infectious diseases. Respiratory protection program managers, healthcare providers, and end users should understand how proper respirator fit and use can decrease skin irritation, as well as how
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