Hepatitis E — Worldwide/Unknown
Background
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Hepatitis E is a liver disease caused by infection with a small, non-enveloped, single-stranded RNA virus known as hepatitis E virus (HEV). Of 4 major HEV genotypes which infect humans, genotypes 1 and 2 are endemic and responsible for waterborne epidemics. Genotypes 3 and 4 are associated with zoonotic HEV infections transmitted to humans through consumption of raw or undercooked infectious pork and game products, and very rarely shellfish, or by contact with
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