PRO/EDR> Zika virus (16): Americas, Asia, research, observations

Zika virus — United States
Abstract
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Because of global spread of Zika virus, accurate and high-throughput diagnostic immunoassays are needed. We compared the sensitivity and specificity of 5 commercially available Zika virus serologic assays to the recommended protocol of Zika virus IgM-capture ELISA and plaque-reduction neutralization tests. Most commercial immunoassays showed low sensitivity, which can be increased.

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[The low sensitivity is a significant concern.