PRO/AH/EDR> Powassan virus encephalitis – USA

Encephalitis — United States
Solomon IH, Spera KM, Ryan SL et al. Fatal Powassan encephalitis (deer tick virus, lineage ii) in a patient with fever and orchitis receiving rituximab. JAMA Neurol. 2018;75(6):746-750. doi: 10.1001/jamaneurol.2018.0132. [Epub ahead of print]
Key Points
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Question: What is the most efficient way to diagnose Powassan encephalitis in an immunocompromised patient?
Findings: In this case report of a patient with fatal Powassan encephalitis with negative serology, diagnosis was