Yellow Fever — Angola
Given that we have a highly effective yellow fever vaccine that confers lifelong immunity with one dose, why is yellow fever still a problem? Much of the answer comes down to vaccine supply and demand.
The 17D vaccine is a “legacy” vaccine produced in embryonated chicken eggs using technology that has changed little since the 1940s, when the seed-lot system was introduced. 3 17D substrains (17D-204, 17DD, and 17D-213) are used as vaccines. They have minor differences in genome sequences,
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