PRO/AH/EDR> Yellow fever: vaccine efficacy, reduced doses

Yellow Fever — Angola
Highlights
– Seroconverters to yellow fever (YF) vaccine in reduced doses remained seropositive 8 years later.
– This applies equally well to doses from 27 476 IU down to 31 IU.
– This study supports the minimum dose required by WHO, 1000 IU.
– This information is crucial when use of fractional YF vaccine is considered.
Abstract
In 2009, Bio-Manguinhos conducted a dose-response study with the yellow fever vaccine, administering the vaccine in the usual mean dose of 27 476 IU (full