Zika virus — Worldwide/Unknown
Julia A. Brown, Gursewwak Singh, Joshua A. Acklin, Silviana Lee, James E. Duehr, Anupa N. Chokola et al. Dengue Virus Immunity Increases Zika Virus-Induced Damage During Pregnancy.
Highlights
– Dengue-specific antibodies can enhance Zika virus pathogenesis during pregnancy
– Enhancement of Zika pathogenesis was observed in the placenta, not in the fetus
– Placental damage was associated with an increase in infected trophoblasts
– This process was found to be FcyR mediated
Zika virus
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