Influenza — Worldwide/Unknown
[Penttinen P, Pebody R. Euro Surveill. 2015;20(22):pii=21148.]
Clinical case definitions used for surveillance struggle to satisfy 2 challenging and potentially conflicting needs — sensitivity and specificity. A more sensitive case definition is useful to estimate disease burden and identify outbreaks. It will identify a larger proportion of the true cases, but often at the cost of finding a large number of cases due to other causes. A more specific case definition, however, will provide a
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