PRO/AH/EDR> Ebola Update (14): News, Research, Vaccine

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PRO/AH/EDR> Ebola update (14): news, research, vaccine

April 10, 2017 editor Global Disease Alerts

Ebola -- Worldwide/Unknown- Therapeutic approach4 Apr 2017: Topoisomerase II inhibitors induce DNA damage-dependent interferon responses circumventing Ebola virus immune evasion[Citation. Luthra P, Aguirre S, Yen BC, et al. Topoisomerase II inhibitors induce DNA damage-dependent interferon responses circumventing Ebola virus immune evasion. mBio 2017; 8(2): e00368-17.Abstract. Ebola virus (EBOV) protein VP35 inhibits production of interferon alpha/beta (IFN) by blocking RIG-I-like receptor signaling Read more [...]

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