PRO/EDR> Mycoplasma & ureaplasma – USA: fatal hyperammonemia, organ transplant

Hospital-Related Infection — Worldwide/Unknown
“Hyperammonemia syndrome is a fatal complication affecting immunosuppressed patients. Frequently refractory to treatment, it is characterized by progressive elevations in serum ammonia of unknown etiology, ultimately leading to cerebral edema and death. In mammals, ammonia produced during amino acid metabolism is primarily cleared through the hepatic production of urea, which is eliminated in the kidney. _Ureaplasma_ species, commensals of the urogenital tract, are Mollicutes dependent on urea