Archive for Global Disease Alerts

PRO/AH/EDR> COVID-19 update (477): animal, Sweden, mink, spread, genotyping

COVID-19 — Sweden

PRO/AH/EDR> Eastern equine encephalitis – North America (24): USA (FL) horse

Eastern Equine Encephalitis -- United StatesOfficials at the Florida Department of Agriculture and Consumer Services (FDACS) have confirmed a deceased horse from a private facility in Alachua County tested positive for Eastern equine encephalomyelitis (EEE).The 2-year-old Thoroughbred gelding, who was vaccinated for EEE on 25 Aug 2020, showed clinical signs consisting of fever, depression, listlessness, incoordination, head pressing, aimless wandering, and hind-end weakness before passing away.This Read more [...]

PRO/AH/EDR> COVID-19 update (476): chronic viral shedding, NPIs impact, WHO, global

COVID-19 -- Worldwide/UnknownA stay-at-home order and case investigations instituted weeks before the peak in COVID-19 cases (week of 13 Apr 2020) in Delaware likely contributed to the subsequent decline observed in COVID-19 incidence and associated hospitalization and deaths. As expected, the impact on incidence was not immediate but occurred weeks after measures were implemented, as new cases represented exposure that occurred during previous weeks. Additional steep declines in reports of new cases Read more [...]

PRO/AH/EDR> COVID-19 update (475): animal, Denmark, mink, spike protein sequences

COVID-19 -- DenmarkDenmark set off alarm bells this week with its announcement that it is culling the nation's entire mink herd -- the largest in the world -- to stop spread of the SARS-CoV-2 virus in the prized fur species because of potentially dangerous mutations.Inter-species jumps of viruses make scientists nervous -- as do suggestions of potentially significant mutations that result from those jumps. In this case, Danish authorities say they've found some genetic changes that might undermine Read more [...]

PRO/AH/EDR> Avian influenza (78): Germany (SH, MV) poultry, wild bird, HPAI H5N8, H5N5, OIE

Avian Influenza H5N8 -- GermanyInformation received on [and dated] 5 Nov 2020 from Dr. Dietrich Rassow, Director for Animal Health and Animal Welfare, Chief Veterinary Officer, Directorate of Animal Health and Animal Welfare, Federal Ministry of Food and Agriculture, Berlin, GermanySummaryReport type: Immediate notificationDate of start of the event: 4 Nov 2020Date of confirmation of the event: 4 Nov 2020Reason for notification: Recurrence of a listed diseaseDate of previous occurrence: 13 May Read more [...]

PRO/AH/EDR> COVID-19 update (474): remdesivir, vaccine induced herd immunity, WHO, global

COVID-19 -- Worldwide/UnknownAbstract--------BackgroundRemdesivir is an RNA polymerase inhibitor with potent antiviral activity in vitro and efficacy in animal models of coronavirus disease 2019 (COVID-19).MethodsWe conducted a randomized, open-label, phase 3 trial involving hospitalized patients with confirmed SARS-CoV-2 infection, oxygen saturation of 94% or less while they were breathing ambient air, and radiologic evidence of pneumonia. Patients were randomly assigned in a 1:1 ratio to receive Read more [...]

PRO/PL> Undiagnosed disease, plantain – India: (KL)

Other Plant Disease -- IndiaAn unidentified disease affected plantain bananas in Wayanad [district]; [it] caused the 3-month-old saplings to break and collapse. The Agriculture Department officials inspected the site.--Communicated by:ProMED-mail[A number of banana (_Musa_ species and hybrids) pathogens have been reported from the region, including, for example, _Banana bunchy top virus_, as well as the fungal diseases of black and yellow sigatoka (_Mycosphaerella_ species) and Panama disease (_Fusarium Read more [...]

PRO/AH/EDR> COVID-19 update (473): animal, Denmark, mink, mutation, eradication, RFI

COVID-19 -- DenmarkThe Danish government announced tough new restrictions on Thursday [5 Nov 2020] in the northeast of the country after authorities discovered that a mutated version of the coronavirus in minks was also found in humans.Danish Prime Minister Mette Frederiksen warned that the mutation could threaten the effectiveness of any future vaccine. She said the mutated virus was found to weaken the ability to form antibodies.As a result, 7 municipalities in the north of the country, home to Read more [...]

PRO/AH/EDR> COVID-19 update (472): schools, immunity, mutations, WHO, global

COVID-19 -- Worldwide/Unknown1. Huang C, Wang Y, Li X, et al. Clinical features of patients infected with 2019 novel coronavirus in Wuhan, China. Lancet. 2020; 395(10223): 497-506. doi: 10.1016/S0140-6736(20)30183-5. Epub 2020 Jan 24. Erratum in: Lancet. 2020 Jan 30;: PMID: 31986264; PMCID: PMC7159299; .2. Peng Y, Mentzer AJ, Liu G, et al. Broad and strong memory CD4+ and CD8+ T cells induced by SARS-CoV-2 in UK convalescent individuals following COVID-19. Nat Immunol. 2020; 21(11): 1336-1345. doi: Read more [...]

PRO/AH/EDR> Acute bovine liver disease – Australia: (VI,TS)

Other Animal Disease -- AustraliaAn uncommon but fatal liver disease affecting dairy cattle in Australia's southern and south eastern states is no longer confined to autumn, but has been found to be affecting herds throughout the year.Acute bovine liver disease (ABLD) has periodically affected dairy cows in South Australia, Victoria, New South Wales, and Tasmania -- with up to 83 per cent of a herd affected in June on one dairy farm in south west Victoria and more than 50 per cent of 2 herds affected Read more [...]

PRO/AH/EDR> Ebola update (51): Congo DR (EQ) strategies, antibody

Ebola -- DR CongoThe 10th Ebola outbreak in the Democratic Republic of Congo (DRC), which struck the eastern part of the country between 2018 and early 2020, went on to become the largest in the country's history. The 11th outbreak, currently underway in Équateur province, in the country's west, looks quite different: it progresses at a slow pace, producing small clusters in isolated areas and a lower overall mortality rate. How has the medical response evolved? How can we take advantage of Read more [...]

PRO/PL> Bunchy top, banana – Australia: (QL,NS) alert

Other Plant Disease -- AustraliaBackyard banana growers in south east Queensland and northern New South Wales have been urged to stay alert for one of the world's most damaging banana diseases after dozens of outbreaks. The Australian Banana Growers' Council [ABGC] has responded to hundreds of reports of bunchy top, which almost wiped out the crop in northern NSW and southern Queensland last century.The council runs the national detection and management program funded by grower levies. Inspectors Read more [...]

PRO/AH/EDR> COVID-19 update (471): animal, Denmark, mink, zoonotic, eradication

COVID-19 -- DenmarkDenmark will cull its entire herd of up to 17 million mink after a mutation of the coronavirus found in the animals spread to humans, posing risk to any possible future vaccine, the prime minister said on Wednesday [4 Nov 2020].Outbreaks at mink farms have persisted in the Nordic country, [which shares with China the top of the world's mink industry], despite repeated efforts to cull infected herds since June [2020].Health authorities found virus strains in humans and in mink that Read more [...]

PRO/EDR> COVID-19 update (470): USA contact tracing, sewage, WHO, global

COVID-19 -- Worldwide/UnknownGiven the pressing need to reopen economic activity prior to the availability of a vaccine, the US and other nations are investing in contact tracing as a core component of the coronavirus disease 2019 (COVID-19) response. An estimated 75% of infected contacts need to be quarantined to contain COVID-19. We evaluated case investigation and contact tracing outcomes in San Francisco, California, during shelter-in-place restrictions.Methods-------San Francisco residents diagnosed Read more [...]

PRO/AH/EDR> COVID-19 update (469): USA (TN) zoo, tiger

COVID-19 -- United StatesA tiger at Zoo Knoxville has tested positive for SARS-CoV-2, the same virus that causes COVID-19 in humans, according to zoo officials.Malayan tigers Arya, Bashir, and Tanvir were experiencing "mild coughing, lethargy, and decrease in appetite." Zoo officials said the animals were tested for "a range of potential causes, including SARS-CoV-2."Zoo officials said test results confirmed that 11-year-old male Bashir tested positive. Officials added confirmatory testing for Arya Read more [...]

PRO/EDR> Influenza (12): WHO global update, Europe (Ukraine), USA

Influenza -- UkraineInformation in this report is categorized by influenza transmission zones, which are geographical groups of countries, areas, or territories with similar influenza transmission patterns.Summary-------- The current influenza surveillance data should be interpreted with caution as the ongoing COVID-19 pandemic has influenced to varying extents health seeking behaviors, staffing/routines in sentinel sites, as well as testing priorities and capacities in Member States. The various Read more [...]

PRO/AH/EDR> Hantavirus – Americas (10): USA (CO)

Hantavirus -- United StatesSR feels lucky to be alive after several visits to the hospital in October [2020]. She had several symptoms that overlap with COVID-19, but was eventually diagnosed with a hantavirus [infection] -- an extremely rare and often fatal disease."I had a high fever, headaches," she said.SR said her symptoms began a few days after a hiking and camping trip on the Colorado Trail. She took a COVID-19 test, which came back negative as her symptoms worsened. "I had low oxygen. I went Read more [...]

PRO/AH/EDR> Avian influenza (77): UK (England) poultry, LPAI H5N2, HPAI H5N8

Avian Influenza -- United KingdomInformation received on 2 Nov 2020 from Dr Christine Middlemiss, Chief Veterinary Officer, DEFRA, Department for Environment, Food and Rural Affairs, London, United KingdomSummaryReport type: immediate notificationDate of start of the event: 30 Oct 2020Date of confirmation of the event: 1 Nov 2020Report date: 2 Nov 2020Date submitted to OIE: 2 Nov 2020Reason for notification: New strain of a listed disease in the countryCausal agent: Low pathogenic avian influenza Read more [...]

PRO/AH/EDR> COVID-19 update (468): animal, Sweden, mink, 1st rep, OIE

COVID-19 -- SwedenIn response to your posting's request for information, I would like to inform you that the following report was sent to the OIE on 29 Oct 2020."Sweden has confirmed the 1st case of infection with SARS-CoV-2 in mink at a farm in the southeast part of the country, in the County of Blekinge. In this area, approximately 20 of Sweden's 40 mink farms are situated. The affected farm has approximately 9500 minks for fur production."Dead minks from the farm were collected and sampled with Read more [...]

PRO/AH/EDR> Avian influenza (76): Germany (HH) wild bird, HPAI H5N8, OIE

Avian Influenza H5N8 -- GermanyInformation received on [and dated] 30 Oct 2020 from Dr Dietrich Rassow, Director for Animal Health and Animal Welfare, Chief Veterinary Officer, Directorate of Animal Health and Animal Welfare, Federal Ministry of Food and Agriculture, Berlin, GermanySummaryReport type: immediate notificationDate of start of the event: 26 Oct 2020Date of confirmation of the event: 30 Oct 2020Reason for notification: recurrence of a listed diseaseDate of previous occurrence: 25 May Read more [...]

PRO/AH/EDR> COVID-19 update (467): vaccines, superspreading events, Ghana, WHO, global

COVID-19 -- GhanaAn unprecedented effort is under way to rapidly develop COVID-19 vaccines, with pharmaceutical companies, academic researchers, and government agencies aiming to compress into several months a process that typically requires at least several years. This work is supported by extraordinary public and private investments and by newly created entities such as Operation Warp Speed. Concurrent with clinical testing of vaccine candidates, new mechanisms are being established to expedite Read more [...]

PRO/AH/EDR> Lumpy skin disease – Viet Nam: (LS,CB) cattle, 1st rep, OIE

Lumpy Skin Disease -- VietnamInformation received on [and dated] 1 Nov 2020 from Dr Dong Pham Van, Director General, Chief Veterinary Officer, Department of Animal Health, Ministry of Agriculture and Rural Development, Hanoi, Viet NamReport type: immediate notificationDate of start of the event: 13 Oct 2020Date of confirmation of the event: 16 Oct 2020Reason for notification: 1st occurrence of a listed disease in the countryCausal agent: Lumpy skin disease virusNature of diagnosis: laboratory Read more [...]

PRO/AH/EDR> Undiagnosed deaths – Nigeria (03): (DE) RFI

Undiagnosed -- NigeriaResidents of Ute Okpu and Idumesa communities in Ika North East Local Government Area, Delta State have been thrown into fear, following the mysterious deaths of over 15 persons within the 18 to 25 years age bracket in the past 2 weeks in the area.But the State Government has assured residents of the area that it would do everything possible to curb the disease. The State Commissioner for Health, Dr. Mordi Ononye gave the assurance on Sunday [1 Nov 2020] when he led a team of Read more [...]

PRO/AH/EDR> African swine fever – Europe (31): Germany (SN) wild boar, spread, OIE

African Swine Fever -- GermanyInformation received on [and dated] 1 Nov 2020 from Dr Dietrich Rassow, Director for Animal Health and Animal Welfare, Chief Veterinary Officer, Directorate of Animal Health and Animal Welfare, Federal Ministry of Food and Agriculture, Berlin, GermanySummaryReport type: immediate notificationDate of start of the event: 30 Oct 2020Date of confirmation of the event: 31 Oct 2020Reason for notification: 1st occurrence of a listed diseaseManifestation of disease: sub-clinical Read more [...]

PRO/AH/EDR> COVID-19 update (466): antibody trial, Kenya, WHO, global

COVID-19 -- Kenya"Abstract---------'Monoclonal antibodies (mAbs) are increasingly being considered as agents to fight severe viral diseases. So far, they have essentially been selected and used on the basis of their virus-neutralizing activity and/or cell-killing activity to blunt viral propagation via direct mechanisms. There is, however, accumulating evidence that they can also induce long-lasting protective antiviral immunity by recruiting the endogenous immune system of infected individuals during Read more [...]

PRO/AH/EDR> Rift Valley fever – Sudan (02): (NO) susp, RFI

Rift Valley Fever -- SudanDoctors say cases and dozens of deaths from the disease have occurred since the August [2020] floods, with cases of malaria and cholera also on the rise.An outbreak of Rift Valley fever has killed dozens of people and infected more than 1000 in Sudan's Northern state, according to local doctors.Doctors told the Guardian the disease has spread across the towns of Merowe, Al Dabbah, and Karima, mainly among cattle herders.However, the Sudanese government has so far denied Read more [...]

PRO/AH/EDR> Pneumonia, ovine – USA: (WA,OR) bighorn sheep

Pneumonia -- United StatesLast week [last of October 2020], wild bighorn sheep herds in Washington and Oregon have been detected with deadly pneumonia, likely caused by a deadly pathogen spread by domestic sheep grazing on public lands. The bighorn are dying slow and painful deaths because they have no natural immunity to the livestock-borne disease.In Washington, the Department of Fish and Wildlife announced that deadly pneumonia had been detected in the Cleman Mountain herd of bighorn sheep, located Read more [...]

PRO/AH/EDR> Rabies (29): Americas (USA) animal, human exposure

Rabies -- United StatesThe Department of Health and Environmental Control (DHEC) has confirmed a raccoon was found near Shivers Green Road and Springdale Road in Ridgeway testing positive for rabies.One person was potentially exposed to saliva from open wounds on their hands and has been referred to their healthcare provider. According to DHEC officials, 2 dogs were exposed and will be quarantined as required [It would have been helpful to know the vaccination status of the dogs. - Mod.TG].If you Read more [...]

PRO/AH/EDR> Equine influenza – USA (05): (CA) wild burros

Equine Influenza -- United StatesThe Riverside County Department of Animal Services today [31 Oct 2020] warned horse owners to beware of an equine influenza outbreak having killed an estimated 3 dozen wild burros in the region.County and state officials are monitoring the outbreak while urging horse owners to check in with their veterinarians about booster vaccines for previously vaccinated animals. Horse owners are also being advised to ensure their animals are not exposed to sick burros by moving Read more [...]

PRO/AH/EDR> COVID-19 update (465): age, South Asia, antibody trial, WHO, global

COVID-19 -- Worldwide/UnknownWHO region (no. countries/territories):Total confirmed cases (new cases in last 24 hours) / Total deaths (new deaths in last 24 hours)------------------------Western Pacific Region (19): 730 379 (3841) / 15 516 (54)European Region (61): 10 803 232 (279 394) / 282 520 (2865)South East Asia Region (10): 9 196 384 (58 046) / 143 582 (687)Eastern Mediterranean Region (22): 3 067 038 (28 807) / 77 893 (703)Region of the Americas (54): 20 311 678 (160 458) / 636 496 (2826)African Read more [...]

PRO/AH> Yellow fever – Africa (13): Zimbabwe, fake cards

Yellow Fever -- ZimbabweAt the main bus terminus in Harare, Zimbabwe's capital, international travelers are tempted with offers of counterfeit travel vaccination certificates. Counterfeit travel vaccination certificates can greatly jeopardize disease control, stated the leaders of the World Health Organization (WHO) African region in a press statement on 30 Oct 2020.A thriving black market there sells fake proof of immunization, said Dr. Integrity Mchechesi in a press release, who works with an innovative Read more [...]

PRO/AH/EDR> Leishmaniasis – North America: dog, new findings

Leishmaniasis -- Worldwide/UnknownExperts are warning that a dangerous flesh-eating parasite could be on its way to Canada. And dogs may be to blame.Veterinarians have started to detect leishmania, a dangerous parasite capable of causing a flesh-eating disease in both animals and humans, in Canadian and US dogs.The parasites, usually spread by sandflies not native to North America, cause the disease leishmaniasis. Some forms of the disease can lead to severe disfigurement or even death. Hundreds Read more [...]

PRO/AH/EDR> COVID-19 update (464): animal, Denmark, mink, control, One Health

COVID-19 -- DenmarkIn North Jutland, foreign labor has been hired to speed up the killing of mink herds with corona infection. This is stated by police inspector Ole Kristensen, who is head of the Local Emergency Response Staff.Just over 100 foreigners are employed to help with the task. According to Kristensen, this is because there are too few people in Denmark who have an understanding of the handling of mink.The Danish Veterinary and Food Administration announced on Twitter on Thursday [29 Oct Read more [...]

PRO/AH/EDR> Yellow fever – Americas (09): Brazil (GO) monkey, fatal

Yellow Fever -- BrazilThe number of monkeys dead of yellow fever in Goias has risen to 7 in one month. The Epidemiological Secretariat [SES] stated that just in Goiania, 200 000 adults and 20 000 children still need to receive doses of the vaccine. Immunization is free and can be done at health centers. [A surprising number for a municipality where vaccination has been recommended for years. - Mod.RNA]State superintendent of health surveillance, Fluvia Amorim, warns of the risk of virus circulation, Read more [...]

PRO/AH/EDR> Eastern equine encephalitis – North America (23): USA, Canada, horse

Eastern Equine Encephalitis -- United StatesA Menominee County horse has died from a mosquito-borne illness. Public Health, Delta & Menominee counties, was notified on Thu 15 Oct 2020 of a horse in Menominee County having died from eastern equine encephalitis (EEE). The horse became ill on 3 Oct 2020.This is the 1st confirmed animal case of EEE in Menominee County this year [2020]. No other animal or human cases of EEE have been confirmed in Menominee County at this time; however, 35 confirmed Read more [...]

PRO/AH/EDR> Lumpy skin disease – Bhutan: (SM) cattle, 1st rep, OIE

Lumpy Skin Disease -- BhutanInformation received on [and dated] 30 Oct 2020 from Dr. Tashi Yangzome Dorji, Director, Department of Livestock, Ministry of Agriculture and Forests, Thimphu, BhutanSummary:Report type: Immediate notificationDate of start of the event: 23 Sep 2020Date of confirmation of the event: 5 Oct 2020Reason for notification: 1st occurrence of a listed disease in the countryCausal agent: Lumpy skin disease virusNature of diagnosis: Clinical, laboratory (basic)This event pertains Read more [...]

PRO/AH/EDR> Avian influenza (75): Netherlands (GE) poultry, HPAI H5N8, OIE

Avian Influenza H5N8 -- NetherlandsInformation received on [and dated] 30 Oct 2020 from Dr. Christianne Bruschke, Chief Veterinary Officer, Agriculture, Nature and Food Quality, Ministry of Agriculture, Nature and Food Quality, The Hague, NetherlandsSummaryReport type: Immediate notificationDate of start of the event: 29 Oct 2020Date of confirmation of the event: 29 Oct 2020Reason for notification: Recurrence of a listed diseaseDate of previous occurrence: 10 Jul 2018Manifestation of disease: Clinical Read more [...]

PRO/AH/EDR> COVID-19 update (463): Brazil (MT) animal, cat, OIE

COVID-19 -- BrazilInformation received on 29 Oct 2020 from Dr. Geraldo Marcos De Moraes, Director, Department of Animal Health and Livestock Supplies, Ministry of Agriculture, Livestock and Supply, Brasilia, BrazilSummaryReport type: Immediate notificationDate of start of the event: 5 Oct 2020Date of confirmation of the event: 16 Oct 2020Report date: 28 Oct 2020Date submitted to OIE: 29 Oct 2020Reason for notification: Emerging diseaseMorbidity: 1 (scale 0 to 5)Mortality: 0 (scale 0 to Read more [...]

PRO/AH/EDR> Bluetongue – Europe (12): Albania, Bosnia & Herzegovina, livestock, st 4, OIE

Bluetongue -- AlbaniaInformation received on [and dated] 23 Oct 2020 from Dr. Keti Margariti, Head, Veterinary and Animal Welfare Sector, Ministry of Agriculture and Rural Development, Tirana, AlbaniaSummaryReport type: Immediate notificationDate of start of the event: 6 Aug 2020Date of confirmation of the event: 28 Aug 2020Report date: 23 Oct 2020Date submitted to OIE: 23 Oct 2020Reason for notification: Recurrence of a listed diseaseDate of previous occurrence: 29 Nov 2016Manifestation of Read more [...]

PRO/EDR> Gonococcal disease: rapid point-of-care testing, targeted therapy

Antimicrobial resistance -- Worldwide/UnknownBackground: Widespread ceftriaxone antimicrobial resistance (AMR) threatens _Neisseria gonorrhoeae_ (NG) treatment, with few alternatives available. AMR point-of-care tests (AMR POCT) may enable alternative treatments, including abandoned regimens, sparing ceftriaxone use. We assessed cost-effectiveness of 5 hypothetical AMR POCT strategies: A-C included a 2nd antibiotic alongside ceftriaxone; D and E consisted of a single antibiotic alternative, compared Read more [...]