COVID-19 — United Kingdom
“Host-mediated lung inflammation is present(1), and drives mortality(2), in critical illness caused by Covid-19. Host genetic variants associated with critical illness may identify mechanistic targets for therapeutic development.(3) Here we report the results of the GenOMICC (Genetics of mortality in critical care) genome-wide association study(GWAS) in 2244 critically ill COVID-19 patients from 208 UK intensive care units (ICUs). We identify and replicate novel genome-wide significant
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