Lyme Disease — United States
“The bacterial pathogen responsible for causing Lyme disease, _Borrelia burgdorferi_, is an atypical Gram-negative spirochete that is transmitted to humans via the bite of an infected _Ixodes_ tick. In diderms [having 2 cell membranes], peptidoglycan (PG) is sandwiched between the inner and outer membrane of the cell envelope. In many other Gram-negative bacteria, PG is bound by protein(s), which provide both structural integrity and continuity between envelope layers. Here, we present
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