Tag Archive for PRO/AH/EDR> Yellow fever vaccines: fractional dose effective

PRO/AH/EDR> Yellow fever vaccines: fractional dose effective

Yellow Fever -- UgandaSummary-------BackgroundStocks of yellow fever vaccine are insufficient to cover exceptional demands for outbreak response. Fractional dosing has shown efficacy, but evidence is limited to the 17DD substrain vaccine. We assessed the immunogenicity and safety of 1/5 fractional dose compared with standard dose of 4 WHO-prequalified yellow fever vaccines produced from 3 substrains.MethodsWe did this randomised, double-blind, non-inferiority trial at research centres in Mbarara, Read more [...]